The Postdoctoral Associate will join the dry lab division of the Laboratory of Human Genetics of Infectious Diseases and participate in the development of novel computational approaches to detect, predict and prioritize genetic variants that could be deleterious and disease-causing. Responsibilities include utilizing existing bioinformatics tools, integrating various biological data, and encoding important biological events for the development of advanced new approaches to decipher the unrevealed role of novel genetic variants in human diseases. Currently, the lab has over 10,000 exome/genome sequenced individuals from a wide range of infectious disease projects. The Postdoctoral Associate will have opportunities to work with the wet-bench investigators across different disease groups to support with functional predictions of the genetic variants and high-throughput genomics/transcriptomics data analyses. Additional responsibilities may include various bioinformatics-related work, including maintaining and updating the in-house exome/genome variant database and the lab-developed webservers.
Ph.D. in bioinformatics, computational biology, or computer science and previous genomics experience required. Must be familiar with Linux environment and shell script writing/running and have programming experience in Python or equivalent. Must have database/website experience in MySQL and PHP. Prior experience in next-generation sequencing data analyses and/or machine-learning studies is preferred.
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